Drug-Induced Ocular Side Effects with CD-Rom, fifth edition. FT Fraunfelder, FW Fraunfelder. Boston: Butterworth-Heinemann, 2001, 824 pp., $59.95.

The preface to this text tells the reader exactly what to expect: “A ‘quick’ reference book that “boils it down.” The book is intended to serve as a guide for determining if a drug is the cause of an ocular problem.

Its effective organization does, indeed, make this a quick reference book. The format is clear, and a perusal of the “Instruction to Users” makes it easy to follow. Each chapter is dedicated to a specific drug category, and the chapters are divided into sections by class of drug, in alphabetical order. The drugs themselves are also listed, in alphabetical order, by generic name. Each listing gives brief information on international proprietary names, primary use of the drug, possible ocular side effects given various administrations, clinically significant findings, and the most current and or recommended references. There is a significant chapter on “Drugs Used Primarily in Ophthalmology.” (although, one could argue that this should be entitled “Ophthalmic Drugs.”) A comprehensive index organized by side effects is included at the end of the text.

The jewel in this guide is the “Clinical Significance” for each drug. This is a candid discussion including such information as the likelihood of a specific side effect, and whether it is reversible or transitory. Clinical trial information, case reports, and literature references are sometimes given. Additional information on drugs used in combination with one or more drug(s), and how this affects the potential ocular side effects, is sometimes provided. Of special note are occasional clinical pearls on patient management for using drugs that can cause significant ocular side effects and discussions regarding controversial findings.

This is a concise yet complete compilation of reports in one place. It is a practical resource that would complement any eye care professional’s library. While it is not small enough to be pocket-sized, it is definitely portable enough for a practitioner to keep handy. Or, for even more convenience, there is a CD-ROM included, which allows a simple download of the interactive full text onto your office computers and your laptop for “at your fingers” availability.